Target and Indication Investment Memo

Board-ready diligence for go, no-go, and portfolio prioritization decisions.

If you are about to commit a nine-figure budget to a program, you should have a diligence-grade memo that integrates human evidence, mechanism, clinical history, and competitive risk into a single recommendation.

2 to 6 weeks typical delivery Fixed scope procurement friendly Decision artifact not a platform NDA ready internal data optional

What you receive

A 30 to 60 page Target and Indication Investment Memo that leadership can use to defend a decision to governance, partners, or investors.

  • 1

    Clear recommendation

    Go, no-go, or conditional, plus kill criteria and what would change the call.

  • 2

    Human evidence and plausibility

    Genetics and human data integrated with mechanism and translational relevance.

  • 3

    Competitive and failure history

    What has been tried, what failed, and where differentiation is realistic.

Ideal trigger moments

When this is most valuable is right before major capital allocation.

  • Portfolio reviews, deciding what to kill vs double down
  • Pre-trial readiness, validating the biological premise
  • Fundraising, strengthening the human evidence story
  • Partnering and licensing, answering diligence questions early
  • Indication expansion, choosing the best entry point

Deliverable outline

  • Executive decision summary with recommendation and key risks
  • Human evidence, genetics, directionality, and causality
  • Mechanism, pathway position, and translational plausibility
  • Clinical and failure history, readouts and lessons
  • Competitive landscape, crowding, and differentiation paths
  • Modality and tractability, feasibility constraints
  • Indication prioritization and patient stratification logic
  • Risk register plus decision-changing experiments

Process

1) Scope the decision

30 minute kickoff to align on the decision, timeline, and what evidence would change the call.

2) Diligence synthesis

Integrate genetics, biology, trial history, and competitive intelligence into a coherent memo with a risk register.

3) Decision review

Walk leadership through the memo, pressure test assumptions, align on recommendation and next-step actions.

Optional, internal data

If you share internal readouts under NDA, we incorporate them and clearly separate internal vs public evidence.

Fixed-scope pricing

Rapid Kill Screen
2 weeks, brutal clarity on whether the target is worth another dollar.
$30k
Full Investment Memo
4 to 6 weeks, board-ready diligence for a single program decision.
$90k to $150k
Portfolio Rebalance
Multiple programs triaged, ranked, and assigned kill criteria.
$250k+

FAQ

Is this target discovery?

No. This is diligence on a specific decision. If you want to discover novel targets at scale, you want a platform. If you want to decide whether to bet on a target and indication, you want a diligence memo.

How do you handle uncertainty?

We make it explicit. The memo includes evidence quality, assumptions, and what experiments or data would be decision-changing. This is often the most valuable part for governance.

What is the fastest way to try this?

Start with a Rapid Kill Screen on one controversial program. If the output is useful, the Full Investment Memo becomes an easy next step.

Book a diligence scoping call

Send the target, indication, and decision deadline. We will propose the right scope and give a fixed price. If you are prepping a board meeting, portfolio review, fundraising, or partner diligence, this usually pays for itself.

BioInfi, Target and Indication Investment Memo
  Target and Indication Investment Memo

Board-ready diligence for go, no-go, and portfolio prioritization decisions.

If you are about to commit a nine-figure budget to a program, you should have a diligence-grade memo that integrates human evidence, mechanism, clinical history, and competitive risk into a single recommendation.

2 to 6 weeks typical delivery Fixed scope procurement friendly Decision artifact not a platform NDA ready internal data optional

What you receive

A 30 to 60 page Target and Indication Investment Memo that leadership can use to defend a decision to governance, partners, or investors.

  • 1

    Clear recommendation

    Go, no-go, or conditional, plus kill criteria and what would change the call.

  • 2

    Human evidence and plausibility

    Genetics and human data integrated with mechanism and translational relevance.

  • 3

    Competitive and failure history

    What has been tried, what failed, and where differentiation is realistic.

Ideal trigger moments

When this is most valuable is right before major capital allocation.

  • Portfolio reviews, deciding what to kill vs double down
  • Pre-trial readiness, validating the biological premise
  • Fundraising, strengthening the human evidence story
  • Partnering and licensing, answering diligence questions early
  • Indication expansion, choosing the best entry point

Deliverable outline

  • Executive decision summary with recommendation and key risks
  • Human evidence, genetics, directionality, and causality
  • Mechanism, pathway position, and translational plausibility
  • Clinical and failure history, readouts and lessons
  • Competitive landscape, crowding, and differentiation paths
  • Modality and tractability, feasibility constraints
  • Indication prioritization and patient stratification logic
  • Risk register plus decision-changing experiments

Process

1) Scope the decision

30 minute kickoff to align on the decision, timeline, and what evidence would change the call.

2) Diligence synthesis

Integrate genetics, biology, trial history, and competitive intelligence into a coherent memo with a risk register.

3) Decision review

Walk leadership through the memo, pressure test assumptions, align on recommendation and next-step actions.

Optional, internal data

If you share internal readouts under NDA, we incorporate them and clearly separate internal vs public evidence.

Fixed-scope pricing

Rapid Kill Screen
2 weeks, brutal clarity on whether the target is worth another dollar.
$30k
Full Investment Memo
4 to 6 weeks, board-ready diligence for a single program decision.
$90k to $150k
Portfolio Rebalance
Multiple programs triaged, ranked, and assigned kill criteria.
$250k+

FAQ

Is this target discovery?

No. This is diligence on a specific decision. If you want to discover novel targets at scale, you want a platform. If you want to decide whether to bet on a target and indication, you want a diligence memo.

How do you handle uncertainty?

We make it explicit. The memo includes evidence quality, assumptions, and what experiments or data would be decision-changing. This is often the most valuable part for governance.

What is the fastest way to try this?

Start with a Rapid Kill Screen on one controversial program. If the output is useful, the Full Investment Memo becomes an easy next step.

Book a diligence scoping call

Send the target, indication, and decision deadline. We will propose the right scope and give a fixed price. If you are prepping a board meeting, portfolio review, fundraising, or partner diligence, this usually pays for itself.